PANCREATIC CANCER

AND ITS STROMA

   Pancreatic stellate cells support tumor growth by synthesis and remodeling of extracellular matrix and by feeding cancer cells with nonessential amino acids. Although discovered almost twenty years ago, activated pancreatic stellate cells and fibrotic stroma they produce remain largely overlooked in most strategies against pancreatic ductal adenocarcinoma.
   We investigate pancreatic cancer as a complex tissue that consists of cancer cells, tumor- associated activated pancreatic stellate cells
and tumor stroma, focusing on calcium signaling.

>>> TEAM MEMBERS

>>> CURRENT PROJECTS

Group Leader

Monika Jakubowska

monika.jakubowska@uj.edu.pl

PhD Students

recruiting

Undergrad Students

Davinia Arguedas Mateo

Eda Dev

Gabriela Burda

  • “All hands on deck”: the interdisciplinary approach against pancreatic cancer and its fibrotic stroma.

  • Targeting mechanisms of pancreatic cancer resistance against therapy: specific role of tumour microenvironment.

  • Czarny Instagram Ikona

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