Animal facility works at the specific pathogen free (SPF) regime and fulfills all statutory requirements for maintaining and breeding genetically modified mice. It is prepared for maintaining up to 8000 mice and up to 250 rats in the individually ventilated cages and for generation of transgenic mice.
Rooms are fully equipped to perform all animal handling, micromanipulations, microsurgery, and in-vivo imaging under sterile conditions. We have extensive and long-lasting experience in employment of animal models in cancer, immune and stem cell research.
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>>> RESEARCH MODELS
Cell line-derived xenografts and allografts for oncology studies (subcutaneous, disseminated and orthotopic growth; cell suspension, spheroids, single spheroids)
Pharmacokinetic or bioavailability sampling
Leukemia models in humanized mice
Angiogenesis and vascularization analysis (tumors, ischemic tissues, mouse retina model)
Aortic aneurism induction and in-vivo monitoring in mice
Bone marrow or HSC/HSPC/PBMC transplantation