Aortic ckit+ cells contribute to vascular homeostasis
Dr Witold Nowak contributed to a recently published work on the role of aortic ckit+ in murine aorta. Team of Prof. Qingbo Xu at King's College London showed heterogeneity of aortic ckit+ cells using single cell RNASeq, and the role played in homeostasis of healthy and tranplanted blood vessel using lineage tracing animals. Finaly, the team showed the importance of cell metabolism, i.e. glycolysis, in the regulation of endothelial gene expression.
You can find the paper here: https://link.springer.com/article/10.1007%2Fs00018-020-03480-4